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But a waiver on patents would be just the first step in ramping up vaccine supply. вЂњThis marks a major shift in US policy in a pro-public health way,вЂќ says global-health researcher Matthew Kavanagh. The measure is aimed at boosting supplies so that people around the world can get the shots. In a shock move, the US government has announced its support for waiving patent protections for COVID-19 vaccines. Nature | 6 min read US backs waiving patents on vaccines вЂњWe have to accept that people will get infected, will go to hospital and will die from COVID-19 in the future,вЂќ says infectious-diseases epidemiologist James McCaw, who advises the Australian government. In some countries, such as Australia and New Zealand, the response to potential threats is swift and severe - but this cannot be sustained indefinitely.

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The mechanism driving the reaction, how it might develop and how to suppress it are all open questions.ДЄs more people get vaccinated, scientists and health officials are pondering how societies can live with the virus and the level of risk that they are willing to take on. Entombed under concrete, the room contains some of the congealed lava that includes much of the reactor's uranium fuel. вЂњItвЂ™s like the embers in a barbecue pit,вЂќ says nuclear-materials chemist Neil Hyatt. Rising levels of neutrons from an inaccessible room at Chernobyl Nuclear Power Plant indicate that fission reactions are smouldering again at the site of the 1986 disaster. Nature | 6 min read Nuclear reactions smoulder in Chernobyl вЂњItвЂ™s the saddest possible result,вЂќ says neurologist Claudia Testa. But back-to-back announcements from Roche and Wave Life Sciences have dealt a crushing blow to those affected by the disease.

Researchers had hoped that the treatments - known as antisense oligonucleotides (ASOs) - would be a game changer for HD, an incurable genetic condition that affects cognition, behaviour and movement. Two pharmaceutical companies have halted clinical trials of gene-targeting therapies for HuntingtonвЂ™s disease (HD), following the drugsвЂ™ disappointing performance. Credit: Frederic Sadou, ISM/Science Photo Library вЂDevastatedвЂ™ by HuntingtonвЂ™s drug failure A mutant form of huntingtin protein, which causes HuntingtonвЂ™s disease, accumulates in nerve cells.

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